The solution that is optically inactive but chiral with 4 substituents is a meso compound. A meso compound is a molecule with chiral centers but also has an internal plane of symmetry, which results in the overall molecule being optically inactive. This occurs when the substituents on the chiral centers cancel each other out in terms of their effect on the overall molecule's chirality. Therefore, even though the molecule is chiral, it does not rotate plane-polarized light and is optically inactive. **

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In a Fischer projection, the substituents to the left represent the groups that are pointing towards the viewer, while the substituents to the right represent the groups that are pointing away from the viewer. This convention helps to visualize the three-dimensional structure of a molecule in a two-dimensional representation. **

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In a Fischer projection, the substituents that are located to the left are typically the ones with higher priority according to the Cahn-Ingold-Prelog rules, such as groups with higher atomic numbers or multiple bonds. The substituents on the right are usually those with lower priority, like hydrogen atoms or groups with lower atomic numbers. The arrangement of substituents in a Fischer projection helps to determine the stereochemistry of a molecule. **